FMOC-(R)-3-AMINO-4-(2-CYANOPHENYL)BUTANOIC ACID - Names and Identifiers
FMOC-(R)-3-AMINO-4-(2-CYANOPHENYL)BUTANOIC ACID - Physico-chemical Properties
Molecular Formula | C26H22N2O4
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Molar Mass | 426.46 |
Storage Condition | 2-8°C |
FMOC-(R)-3-AMINO-4-(2-CYANOPHENYL)BUTANOIC ACID - Risk and Safety
Hazard Symbols | T - Toxic

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Risk Codes | 25 - Toxic if swallowed
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Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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Hazard Class | IRRITANT |
FMOC-(R)-3-AMINO-4-(2-CYANOPHENYL)BUTANOIC ACID - Introduction
Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric is an organic compound containing an amino group and a (2-cyanophenyl) group. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Molecular formula: C₂ H₂ Nover O₂
-Molecular weight: 365.41g/mol
-Appearance: White or off-white solid
-melting point: about 175-178 ℃
-Solubility: Soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and methylene chloride
Use:
- Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid is a commonly used reagent in the biomedical and chemical fields, used for solid phase synthesis and protein synthesis.
-It can be used as a protecting group for amino acids. During the synthesis of polypeptides and proteins, the protecting group is removed by photolysis or chemical methods.
-It can also be used to prepare bioactive polypeptide analogs and drugs
Preparation Method:
The preparation of Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid can be completed by the following steps:
1. (R)-3-amino -4-(2-cyanophenyl) butyric acid is reacted with Fmoc-Cl and acylated under alkaline conditions to obtain the desired product.
2. Appropriate solvents and reaction conditions can be used to optimize the reaction process, such as using dimethylformamide (DMF) and dimethyl sulfoxide (DMSO) as solvents, and promoting the reaction by stirring and controlling the reaction temperature.
Safety Information:
- Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid is relatively safe under correct use, however, it should be carried out in the laboratory and follow appropriate laboratory regulations and operating procedures.
-Take appropriate personal protective measures, such as wearing gloves and goggles, when handling the compound.
-The toxicity study of this compound is limited, so inhalation and exposure should be avoided as much as possible.
-During handling and storage, it should be separated from other incompatible chemicals and sealed in a dry, low-temperature, dark place.
Last Update:2024-04-09 20:49:11